MASKED LEPROMATOUS LEPROSY. A CLINICAL NOTE

A clinical trial of pefloxacin and ofloxacin in lepromatous leprosy.

A 2-month clinical trial of pefloxacin and ofloxacin in previously untreated multibacillary patients was conducted at the Leonard Wood Memorial Leprosy Research Center, Cebu, the Philippines. Treatment with either pefloxacin or ofloxacin resulted in rapid clinical improvement, in this regard pefloxacin appearing somewhat superior. Reactions and side effects were minimal. Single doses of either ...

A clinical trial of minocycline in lepromatous leprosy.

population injected drugs in the six months before arrest.45 If we assume from our data that 8% of them were HIV positive that gives an estimated total of 203 HIV positive male drug injectors in the sentenced population. The corresponding figures for women (about 168 recent injectors, and 15% HIV positive) suggest a total of 25 HIV positive women in prison. At any time, therefore, the total num...

Localized borderline lepromatous leprosy.

A 48-year-old soldier presented with 3 small leprosy lesions localized over the flexor area of the forearm. There was no nerve thickening and clinically the lesions looked like borderline-tuberculoid leprosy. However, these lesions demonstrated a bacteriological index (BI) of 4+ while no acid-fast bacilli (AFB) could be demonstrated from any other site of the body. A lepromin test was negative....

Borderline lepromatous leprosy.

It is presented a case of borderline lepromatous leprosy with 4 years of evolution and cutaneous lesions of difficult diagnosis in the National Health System. The histopathological evaluation, which was essential for the diagnosis, showed disorganized granulomatous structures and multiple alcohol -acid resistant bacilli. Cases like the one described here are responsible for the contamination of...

Histologic and lymphangiographic studies in patients with clinical lepromatous leprosy.